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Trinity College Dublin

HOEY LAB

MECHANOBIOLOGY RESEARCH GROUP

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Research Focus

Our research focus is to integrate engineering mechanics into the understanding of the molecular basis of orthopaedic physiology and disease. Our research has discovered novel mechanisms by which bone can sense and respond to a biophysical stimulus. In particular, we are focused on determining indirect and direct biophysical regulation of mesenchymal stem cell contributions to bone formation and repair and how this is altered in disease. These platforms have potential to result in new orthobiologics and biomaterials that mimic the beneficial effect of biophysical stimuli and treat orthopaedic diseases such as osteoporosis and osteoarthritis.


News & Highlights

  • 21st January 2017 – Congratulations to PhD candidate Michele Corrigan on receiving 2nd prize in the student competition at the 2017 Bioengineering in Ireland Conference held in Belfast, Northern Ireland. She received this award for her work deciphering the role of TRPV4 in mesenchymal stem cell mechanotransduction.
  • 16th November 2016 - Lab PI, Dr. David Hoey, was highlighted by the Irish Research Council as part of an exhibit at Dublin Castle to promote science to the general public.
  • 14th June 2016 – Lab PI, Dr. David Hoey, was 1 of 18 researchers highlighted by www.siliconrepublic.com to demonstrate the variety of research being conducted across Ireland.

https://www.siliconrepublic.com/innovation/research-science-humanities-irish-research-council

  • 29th April 2016 – Congratulations to PhD candidate Gillian Johnson on receiving 3rd prize in the poster competition at the 2016 UL/NUIG Research Day for her work in Catsper calcium channels.
  • 27th April 2016 – Congratulations to PhD candidate Kian Eichholz on winning the best paper award at the 2016 Crossland Symposium held at Queens University Belfast. The prize is awarded to the best paper from a postgraduate student from the island of Ireland who has completed one year of research in a field related to Mechanical Engineering and is sponsored by Engineers Ireland. Kian’s paper was entitled “Design and Manufacture of an Innovative Biofabrication Method for 3D Tissue Engineering Constructs”
  • 8th March 2016 – Dr. Marie-Noelle Labour, Elena Stavenschi, Kian Eichholz, and Gillian Johnson presented their findings at the 62nd Annual Meeting of the Orthopaedic Research Society in Disneyworld, Florida.
  • 10th December 2015 – Dr. David Hoey received the Marie-Sklodowska Curie 2015 COFUND Excellence Award in recognition of his labs contribution to research into bone mechanobiology. See interview with Dr. Hoey and his team at https://www.youtube.com/watch?v=lm8mJrAegNk
  • 19th November 2015 – Congratulations to Dr. Marie-Noelle Labour, Elena Stavenschi, Kian Eichholz, and Gillian Johnson for getting their abstracts accepted to the 62nd Annual Meeting of the Orthopaedic Research Society which will be held in Disneyland, Florida, USA, 2016.
  • 1st November 2015 – Welcome to Mathieu Riffault, a new Postdoctoral Researcher in our group, who will be investigating the role of the primary cilium in loading-induced bone formation.

Contact Information

Princial Investigator - David A. Hoey

Associate Professor in Biomedical Engineering (Mechanobiology)

Trinity Centre for Bioengineering
Trinity College
Dublin 2
Ireland

Tel: +353 1 8961359
Fax: +353 1 6795554
Email: dahoey@tcd.ie
Web: http://www.mee.tcd.ie/biomaterials/People/DHoey

Page last modified on June 12, 2017
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