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Trinity College Dublin

Martin Holmes


Martin Holmes

Contact Information


Email: holmesms@tcd.ie
Tel: +353-1-8964214
LinkedIn: https://ie.linkedin.com/in/martinsholmes


Biographical Information


Martin graduated in 2011 with an honours degree in Biomedical Engineering from the University of Limerick. He then moved to Trinity College Dublin to carry out research under the supervision of Prof. Richard Reilly. Martin's research focuses on the development of a new electronic monitoring system for inhaler devices. The system can provide personalised objective feedback on inhaler adherence and technique to asthma/COPD patients and healthcare professionals.


To find out more about Martin's research, watch the following short 3 minute video.




Research Interests


  • Medication Adherence
  • Signal Processing of Biomedical Signals
  • Medical Device Design
  • Clinical Trials
  • Inhaler Devices
  • Data Analytics
  • Asthma/COPD


Publications

Journal Papers

  • An Acoustic-Based Method to Detect and Quantify the Effect of Exhalation into a Dry Powder Inhaler. Martin S. Holmes, Jansen Seheult, Peter O'Connell, Shona D'Arcy, Carsten Ehrhardt, Ann Marie Healy, Richard W. Costello, Richard B. Reilly, Journal of Aerosol Medicine & Pulmonary Drug Delivery. 28 (2015) 247-253. (http://www.ncbi.nlm.nih.gov/pubmed/25393346)
  • Acoustic analysis of inhaler sounds from community dwelling asthmatic patients for automatic assessment of adherence. Martin S. Holmes, Shona D'Arcy, Richard W. Costello, Richard B. Reilly, IEEE Journal of Translational Engineering in Medicine and Health. 2 (2014) 1-10. (http://health.embs.org/articles/acoustic-analysis-inhaler-sounds-community-dwelling-asthmatic-patients-automatic-assessment-adherence/)
  • A method of estimating inspiratory flow rate and volume from an inhaler using acoustic measurements. Martin S. Holmes, Jansen Seheult, Colm Geraghty, Shona D'Arcy, Ultan O'Brien, Gloria Crispino O'Connell, Richard W. Costello, Richard B. Reilly, Physiological Measurement. 34 (2013) 903-914. (http://iopscience.iop.org/0967-3334/34/8/903/)
  • A Method to Assess Adherence in Inhaler Use through Analysis of Acoustic Recordings of Inhaler Events. Shona D'Arcy, Elaine MacHale, Jansen Seheult, Martin S. Holmes, Cian Hughes, Imran Sulaiman, Deirdre Hyland, Conor O'Reilly, Senan Glynn, Thekra Al-Zaabi, John McCourt, Terence Taylor, Frank Keane, Isabelle Killane, Richard B. Reilly, Richard W. Costello, PLOS ONE (2014).(http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0098701)
  • The Acoustic Features of Inhalation can be Used to Quantify Aerosol Delivery from a Diskus™ Dry Powder Inhaler. Jansen N. Seheult, Peter O’Connell, Kee Chun Tee, Tariq Bholah, Hasan Al Bannai, Imran Sulaiman, Elaine MacHale, Shona D’Arcy, Martin S. Holmes, David Bergin, Emer Reeves, Richard B. Reilly, Gloria Crispino-O’Connell, Carsten Ehrhardt, Anne Marie Healy, Richard W. Costello, Pharmaceutical Research (2014).(http://link.springer.com/article/10.1007/s11095-014-1371-x)

Conference Papers

  • An acoustic method of automatically evaluating patient inhaler technique. Martin S. Holmes, Shona D'Arcy, Richard W. Costello, Richard B. Reilly, Proceedings of the 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Osaka, Japan. 2013. (http://www.ncbi.nlm.nih.gov/pubmed/24109939)
  • Using acoustics to estimate inspiratory flow rate and drug removed from a dry powder inhaler. Martin S. Holmes, Jansen Seheult, Colm Geraghty, Shona D'Arcy, Richard W. Costello, Richard B. Reilly, Proceedings of the 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Osaka, Japan. 2013. (http://www.ncbi.nlm.nih.gov/pubmed/24111322)
  • Automatic identification and accurate temporal detection of inhalations in asthma inhaler recordings. Martin S Holmes, Marine Le Menn, Shona D'Arcy, Viliam Rapcan, Elaine MacHale, Richard W Costello, Richard B Reilly, Proceedings of the 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, San Diego,USA. 2012. (http://www.ncbi.nlm.nih.gov/pubmed/23366456)
  • An acoustic method to automatically detect pressurized metered dose inhaler actuations. Terence E Taylor, Martin S Holmes, Imran Sulaiman, Shona D'Arcy, Richard W Costello, Richard B Reilly, Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, USA. 2014. (http://www.ncbi.nlm.nih.gov/pubmed/25571019)
  • Influences of gender and anthropometric features on inspiratory inhaler acoustics and peak inspiratory flow rate. Terence E Taylor, Martin S Holmes, Imran Sulaiman, Richard W Costello, Richard B Reilly, Proceedings of the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Milan, Italy. 2015.

Conference Abstracts

  • Objective measurement of inhaler peak inspiratory flow rate (PIFR) using non-contact acoustic methods. Martin S. Holmes, Terence Taylor, Richard W. Costello, Richard B. Reilly, 20th International Society of Aerosol Medicine (ISAM) Conference, Munich, Germany. 2015.
  • Exhaling into the mouthpiece of a Diskus inhaler: An acoustic method to detect this critical error and quantification of its effect. Martin S. Holmes, Jansen Seheult, Peter O'Connell, Shona D'Arcy, Carsten Ehrhardt, Ann Marie Healy, Richard W. Costello, Richard B. Reilly, American Thoracic Society (ATS) Conference, San Diego, USA. 2014.
  • Acoustic analysis of inhaler sounds can be used to automatically evaluate patient inhaler technique. Martin S. Holmes, Terence Taylor, Jansen Seheult,Shona D'Arcy, Richard W. Costello, Richard B. Reilly, 20th Annual Bioengineering in Ireland (BINI) conference, Limerick, Ireland. 2014.
  • An acoustic method of predicting peak inspiratory flow (PIF) and total emitted dose (TED) from a dry powder inhaler. Martin S. Holmes, Jansen Seheult, Colm Geraghty, Shona D'Arcy, Richard W. Costello, Richard B. Reilly, 19th Annual Bioengineering in Ireland (BINI) conference, Enfield, Co. Meath, Ireland. 2013.
  • Exhaling into a Diskus inhaler before inhalation has a detrimental effect on subsequent drug delivery. Martin S. Holmes, Jansen Seheult, Peter O'Connell, Shona D'Arcy, Carsten Ehrhardt, Ann Marie Healy, Richard W. Costello, Richard B. Reilly, Irish Thoracic Society (ITS) Conference, Derry, Ireland. 2013.
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